I am running Skype 220.127.116.11 on Windows vista SP 2 (64 bit).
I keep getting the pop up advising me that there is a upgrade available for Skype. When I start the upgrade it fails with the following message
Unable to read c:\Program Data\Skype\...ae1d8\skypesetup...18.104.22.168.msi
and also i try the skypefull it's same problem
Then I get an Installation failed message with a code of 1603.
I get the same results when I try to reinstall Skype from the main Skype Download page as well.