What anti-virus application or security suite is installed?
Please test with Portable Version 18.104.22.168...
Make sure Content Advisor is turned off in Internet Explorer.
Glad to hear that.
Exit Skype : From the system tray >> right click on the skype icon and click "Quit"
Press WinKey + R to open the Run window
WinKey (the button is located between the left Ctrl and Alt with the Windows logo)
type: %programdata%\Skype\Apps and press Enter
Rename the folder login to login1.
Again Press WinKey + R
type: %appdata% and press Enter
Rename the folder Skype to Old_Skype
Try to uninstalling Skype with Revo Uninstaller
Download and Run Revo
Right Click on Skype and Select Uninstall
Windows Installer Launched >> Click Yes
Check Advanced Button >> Click Scan
In Found Leftover Registry itms window >> Click Select All >> Then Click Delete >> Next
In Found Leftover files and folders window >> Click Select All >> Then Click Delete >> Next
Now try reinstalling latest Skype with this link:
You can make a backup by following the instructions below.